Nebulized Delivery of the MAPKAP Kinase 2 Peptide Inhibitor MMI-0100 Protects Against Ischemia-Induced Systolic Dysfunction
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چکیده
منابع مشابه
The protein kinase 2 inhibitor tetrabromobenzotriazole protects against renal ischemia reperfusion injury
Protein kinase 2 (CK2) activation was reported to enhance reactive oxygen species production and activate the nuclear factor κB (NF-κB) pathway. Because oxidative stress and inflammation are critical events for tissue destruction during ischemia reperfusion (I/R), we sought to determine whether CK2 was important in the renal response to I/R. Mice underwent 25 min of renal ischemia and were then...
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ژورنال
عنوان ژورنال: International Journal of Peptide Research and Therapeutics
سال: 2016
ISSN: 1573-3149,1573-3904
DOI: 10.1007/s10989-015-9507-3